5 EASY FACTS ABOUT P62 DESCRIBED

Keap1 also reversibly translocates to the p62-gels inside a p62-binding dependent trend to activate the transcription component Nrf2. Mice deficient for Atg8-interaction-dependent selective autophagy exhibit that impaired turnover of p62-gels causes Nrf2 hyperactivation in vivo. These results indicate that p62-gels are usually not easy substrates f